Diffuse Large B-Cell Lymphoma (DLBCL) is the most common non-Hodgkin lymphoma worldwide. DLBCL is fatal without treatment, but early detection and therapy can cure up to 70% of patients. The current best prognostic classification, the National Comprehensive Cancer Network International Prognostic Index, is insufficient to guide therapeutic decision-making for individual patients. No tumor-intrinsic prognostication...
This collection contains clinical data and computed tomography (CT) from 137 head and neck squamous cell carcinoma (HNSCC) patients treated by radiotherapy. For these patients a pre-treatment CT scan was manual delineated by an experienced radiation oncologist of the 3D volume of the gross tumor volume. This dataset refers to the "H&N1" dataset of the study published in Nature Communications (http://doi.org/10.1038/ncomms5006). At...
This collection contains FDG-PET/CT and radiotherapy planning CT imaging data of 298 patients from four different institutions in Québec with histologically proven head-and-neck cancer (H&N) All patients had pre-treatment FDG-PET/CT scans between April 2006 and November 2014, and within a median of 18 days (range: 6-66) before treatment. Dates in the TCIA images have been changed in the interest of de-identification;...
This collection combines advanced molecular imaging treatment response assessment through pre- and post-treatment FDG PET/CT scans with therapy of advanced head and neck cancer, including chemo-radiation therapy with and without addition of an EGFR inhibitor molecular targeted agent (Cetuximab).
The Head-Neck Cetuximab collection consists of a subset of image data from RTOG 0522, which was randomized phase...
Researchers will have the unique opportunity to visualize how head-and-neck squamous cell carcinoma (HNSCC) patients’ 3D CT image data changes with radiotherapy between pre-treatment, mid-treatment, and post-treatment. They will also have the advantage to receive additional information such as a) photon energy, b) number of arcs for volumetric modulated arc radiotherapy (VMAT) therapy, c) tumor volume and location,...
This collection consists of 230 cases of glioblastoma and low-grade glioma patients treated with surgery and adjuvant radiotherapy at Massachusetts General Hospital. The patients underwent routine post-surgical MRI examination by acquiring two MR sequences, contrast enhanced 3D-T1 and 2D multislice-T2 FLAIR required to define target volumes for radiotherapy treatment. CT scans were acquired after diagnostic imaging...
This collection contains MR images of both low and high grade glial brain lesions. Data includes post-contrast T1w images with co-registered volumes of dynamic susceptibility contrast (DSC) MR images in DICOM format. Binary regions of interest are also included, in DICOM format, of the lesion, arterial input function, normal appearing white matter, normal appearing cerebral cortex, and whole brain. The data was provided...
The standardization of dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) has been confounded by a lack of consensus on DSC-MRI methodology for preventing potential relative cerebral blood volume (CBV) inaccuracies, including the choice of acquisition protocols and postprocessing algorithms. Therefore, a digital reference object (DRO) was developed using physiological and kinetic parameters...
This collection is comprised of 390 patients who presented with vestibular schwannoma (VS, n=73), trigeminal neuralgia (TGN, n=119) or metastatic disease (M, n=198, 4-26 metastases) and were subsequently treated with Gamma Knife (Elekta AB, Stockholm, Sweden) stereotactic radiosurgery. For each patient, the treatment indication is designated with a suffix on their patient ID (VS, TGN or M).
All patients are provided...
This collection comprises a total of 28 3 Tesla T1-weighted, T2-weighted, Diffusion weighted and Dynamic Contrast Enhanced prostate MRI along with accompanying digitized histopathology (H&E stained) images of corresponding radical prostatectomy specimens. The MRI scans also have a mapping of extent of prostate cancer on them [10.1002/jmri.24975]. Each surgically...
